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Visit-to-Visit Variability of Blood Pressure and Coronary Heart Disease, Stroke, Heart Failure, and Mortality A Cohort Study. Paul Muntner, PhD; Jeff Whittle, MD; Amy I. Lynch, PhD.
Variability of blood pressure (BP) across outpatient visits is frequently dismissed as random fluctuation around a patient's underlying BP. During follow-up, 1194 fatal CHD or nonfatal MI events, 1948 deaths, 606 strokes, and 921 heart failure events occurred. After multivariable adjustment, including for mean SBP, the hazard ratio comparing participants in the highest versus........

Regulating Antibiotics in an Era of Resistance: The Historical Basis and Continued Need for Adequate and Well-Controlled Investigations Scott H. Podolsky, MD, and John H. Powers III, MD.
Two bills introduced in Congress (the Promise for Antibiotics and Therapeutics for Health Act and the Antibiotic Development to Advance Patient Treatment Act of 2013 in the 21st Century Cures Act) propose changes in the regulatory approval of new antibiotics in the context of attempts to reengage industry..............